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The term that refers to the study of bones is "Oste/o." In medical terminology, "osteology" is the branch of biology that deals with the study of the skeleton and bony structures. The prefix "oste/o-" comes from the Greek word "osteon," meaning bone, and is widely used in terms related to bones and their conditions, such as "osteoporosis" (a condition characterized by reduced bone density).

The other prefixes relate to different anatomical structures or conditions. For example, "rheumat/o" pertains to rheumatism or diseases that affect joints and connective tissues. "Ortho/o" is used in terms related to alignment and straightening, particularly in orthopedics, which focuses on the musculoskeletal system but not specifically on bones alone. "Chondr/o" refers to cartilage, the flexible connective tissue found in many parts of the body, but does not encompass the study of bones themselves. Thus, "Oste/o" is the correct choice for indicating the study of bones.